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Mexican Ground Beef Casserole

Using easy-to-find store bought ingredients and needing very little prep, this tasty Mexican Ground Beef Casserole is a winner!

Here’s a recipe that’s simple, delicious, and made with only 6 ingredients, including ground beef (of course), store bought salsa, beans, cheese, and crushed tortilla chips. And you won’t believe how flavorful it is. In fact, it tastes a lot like beef enchiladas—but sooo much easier to make!

About The Meat

My recipe below uses ground beef, and I tend to reach for 85% lean. But you could absolutely use whatever kind you like. You could even use ground pork, chicken, or turkey—or a combination.

To cook the beef—or whatever meat you choose—I use a slightly unusual method that gets a nice brown crust on it, which means extra flavor. It’s really easy and described in the recipe, but you can read more about it in my post on how to cook ground beef.

(And if you like ground beef casseroles, you might also like this cheesy Ground Beef Casserole with noodles and this Ground Beef and Rice Skillet.)

About The Add-ins

Whatever kind of salsa you like, dump it in. Whatever kind of tortilla chips you have, crush them up. And the same goes for the beans—I used pintos for the recipe you see in the photo, but this is also good with black beans, kidney beans, and even white beans or garbanzos, although garbanzos will lack a little of the Mexican vibe. So use whichever you like.

Also for the Mexican vibe, I like to use a Mexican shredded cheese blend to top my casserole. But really any shredded cheese will work—Cheddar, jack, even mozzarella. You could also use crumbled cheese instead of shredded. Crumbled queso fresco, for example, would be great.

(Here’s another one with a similar vibe, my Southwest Chicken Skillet.)

Add Toppings If You Like

Although the casserole doesn’t need it, you can add and enhance if you want to. My photo shows it topped with tomatoes, scallions, and more crushed tortilla chips. But chopped cilantro, sour cream, diced avocado, and sliced olives would also be great. You can even offer a selection of toppings and let diners customize their individual plates.

No matter how you configure it, I know you’ll love it. This one is easy and really tasty—a definite dinner winner.




Mexican Ground Beef Casserole

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  • Author: Christine Pittman
  • Prep Time: 8 minutes
  • Cook Time: 55 minutes
  • Total Time: 1 hour 3 minutes
  • Yield: 46 servings 1x
  • Category: Entrée
  • Method: Baked
  • Cuisine: Mexican


Using easy-to-find store bought ingredients and needing very little prep, this tasty Mexican dinner is a winner! And while it’s absolutely delicious as-is, you also enhance it with your favorite toppings, including tomatoes, scallions, chips, cilantro, sour cream, avocado, and olives!


  • 1 Tbsp. olive oil
  • 1 1/4 lb. ground beef (see note)
  • 2 cups salsa
  • 1 16-oz. can beans, drained
  • 4 cups tortilla chips, crushed
  • 1 1/2 cups shredded Mexican cheese blend (see note)


  1. Preheat the oven to 350°F. Coat a 9×13-inch pan or 2-quart baking dish with nonstick spray and set aside.
  2. Meanwhile, in a very large skillet, heat the oil over medium heat. Add the beef and, using a spatula, press the beef into an even, flat layer in the pan. Let cook untouched for 4 minutes.
  3. Stir the beef, breaking it up, and continue cooking until the meat is cooked through, about 3 minutes.
  4. Stir in the salsa and bring to a boil. Cook, stirring occasionally, until the liquid is cooked off, about 20 minutes.
  5. Add the beans and cook until heated through, about 3 minutes. Remove from the heat.
  6. Add the tortilla chips to the prepared pan or baking dish. Top with the beef mixture and cheese.
  7. Bake until heated through, about 20 minutes.


Note: For the beef, I like to use 85% lean, but whatever you like will work for this recipe. You can even use ground pork, chicken, or turkey. And for the cheese, I like a Mexican cheese blend, but really any kind of shredded cheese will work.